Table 4.
Top 20 InterPro Domains and SCOP Superfamily Hits for the Mouse Secretome
|
InterPro Domains |
||||
|---|---|---|---|---|
| Domain |
No. |
Description |
||
| IPR000561 | 103 | EGF-like domain | ||
| IPR001254 | 101 | Serine protease, trypsin family | ||
| IPR001314 | 97 | Chymotrypsin serine protease, family S1 | ||
| IPR003599 | 63 | Immunoglobulin subtype | ||
| IPR003006 | 60 | Immunoglobulin/major histocompatibility complex | ||
| IPR001687 | 57 | ATP/GTP-binding site motif A (P-loop) | ||
| IPR001881 | 54 | EGF-like calcium-binding | ||
| IPR000087 | 53 | Collagen triple helix repeat | ||
| IPR000152 | 42 | Aspartic acid and asparagine hydroxylation site | ||
| IPR000379 | 41 | Esterase/lipase/thioesterase, active site | ||
| IPR001611 | 31 | Leucine-rich repeat | ||
| IPR001811 | 31 | Small chemokine, interleukin-8-like | ||
| IPR001839 | 31 | Transforming growth factor beta (TGFb) | ||
| IPR003598 | 31 | Immunoglobulin C-2 type | ||
| IPR001128 | 30 | Cytochrome P450 | ||
| IPR003591 | 29 | Leucine-rich repeat, typical subtype | ||
| IPR000130 | 26 | Neutral zinc metallopeptidase | ||
| IPR000884 | 25 | Thrombospondin, type I | ||
| IPR001304 | 25 | C-type lectin | ||
|
IPR001438
|
25
|
Type II EGF-like signature
|
||
| SCOP Superfamilies |
||||
|---|---|---|---|---|
| Domain |
No. |
Description |
||
| 50494 | 98 | Trypsin-like serine proteases | ||
| 57196 | 90 | EGF/laminin | ||
| 48726 | 87 | Immunoglobulin | ||
| 47266 | 52 | 4-helical cytokines | ||
| 57501 | 51 | Cystine-knot cytokines | ||
| 53474 | 46 | alpha/beta-Hydrolases | ||
| 52540 | 34 | P-loop containing nucleotide triphosphate hydrolases | ||
| 49899 | 33 | Concanavalin A-like lectins/glucanases | ||
| 56436 | 33 | C-type lectin-like | ||
| 54117 | 31 | Interleukin 8-like chemokines | ||
| 48264 | 29 | Cytochrome P450 | ||
| 55486 | 26 | Metalloproteases (zincins), catalytic domain | ||
| 53300 | 24 | Integrin A (or I) domain | ||
| 50814 | 23 | Lipocalins | ||
| 53448 | 23 | Nucleotide-diphospho-sugar transferases | ||
| 57392 | 23 | Defensin-like | ||
| 57467 | 23 | Ovomucoid/PCI-1 like inhibitors | ||
| 54001 | 23 | Cysteine proteinases | ||
| 57535 | 22 | Complement control module/SCR domain | ||
|
49842
|
21
|
TNF-like
|
||
