Computational Discovery of Internal Micro-Exons

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3
Figure 3

Spliced alignment correction algorithm. Combinations of consensus donor and acceptor splice sites adjacent to the flawed alignment boundaries are used to enumerate all potential micro-exons within the cDNA sequence. One of the potential micro-exons is localized to the genomic DNA intervening the alignment segments, flanked by consensus splice sites, yielding the identity and position of the newly discovered micro-exon.

This Article

  1. Genome Res. 13: 1216-1221

Preprint Server