Differential Expansion of Zinc-Finger Transcription Factor Loci in Homologous Human and Mouse Gene Clusters

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 7
Figure 7

Expression of HSA19q13.2 ZNF gene family members in human tissues. Northern blots of poly (A)+ RNA from whole tissues was hybridized to gene-specific probes for each family member. The gene names are indicated at the left and are grouped according to evolutionary relationships between the loci. Approximate molecular weights of transcripts are indicated in the middle of each panel. The blots used for these studies were also rehybridized to a probe for human β-actin, with a representative set of results shown in the bottom panel. *: The Northern blots shown hybridized with the ZNF404 and ZNF283 probes were identical to the others except for the substitution of a uterus RNA sample (for ZNF404 and ZNF283) instead of ovary RNA (all others) in the lane indicated.

This Article

  1. Genome Res. 13: 1097-1110

Preprint Server