LineUp: Statistical Detection of Chromosomal Homology With Application to Plant Comparative Genomics

Table 1.

Analysis of Random Data Constructed Under the Null Hypothesis of No Regional Homology

No. marker pairs 50 100 200 400
Method no. prop (SD) no. prop (SD) no. prop (SD) no. prop (SD)
Full D = 0 28 0.06 (0.07) 72 0.05 (0.04) 155 0.05 (0.02) 382 0.05 (0.02)
Full D = 1 81 0.06 (0.05) 350 0.05 (0.03) 2201 0.05 (0.02) 25,529 0.05 (0.01)
Full D = 2 165 0.05 (0.04) 1053 0.05 (0.02) 11,657 0.05 (0.02) >106 NA
FastRunD = 0 23 0.06 (0.08) 54 0.06 (0.04) 120 0.05 (0.03) 293 0.05 (0.02)
FastRunsD = 1 64 0.06 (0.05) 264 0.05 (0.03) 1480 0.05 (0.02) 11,596 0.05 (0.01)
FastRunsD = 2 126 0.05 (0.04) 707 0.05 (0.02) 5527 0.05 (0.02) 61,921 0.05 (0.01)
  • Average number of identified runs, based on 100 data sets.

  • Average proportion of significant runs, based on 100 data sets, under α = 0.05. For each of the 100 data sets, significance was based on 100 Monte Carlo simulations.

  • NA indicates not available; analysis was terminated owing to lack of memory.

This Article

  1. Genome Res. 13: 999-1010

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