Table 2.
Allele Frequency Estimates of Pooled DNA Sample Compared with Observed Allele Frequencies
| Single nucleotide polymorphism markers (R110/Tamra) | Pool 1 32 African-American individuals | Pool 2 32 Asian-American individuals | Pool 3 32 European-American individuals | ||||
| Known (allele) | Measured (mean ± SD) | Known (allele) | Measured (mean ± SD) | Known (allele) | Measured (mean ± SD) | ||
| rs3157 G/A | 0.81 (A) | 0.81 ± 0.007 | 0.55 (A) | 0.53 ± 0.013 | 0.61 (A) | 0.60 ± 0.012 | |
| rs3157 C/T | 0.81 ± 0.007 | 0.52 ± 0.010 | 0.59 ± 0.018 | ||||
| rs688 G/A | 0.48 (A) | 0.47 ± 0.007 | 0.034 (A) | 0.025 ± 0.015 | 0.45 (A) | 0.44 ± 0.005 | |
| rs696 G/A | 0.61 (A) | 0.62 ± 0.006 | 0.41 (A) | 0.44 ± 0.014 | 0.31 (A) | 0.32 ± 0.024 | |
| rs696 C/T | 0.61 ± 0.009 | 0.43 ± 0.006 | 0.35 ± 0.009 | ||||
| rs245 A/T | 0.59 (A) | 0.58 ± 0.015 | 0.55 (A) | 0.54 ± 0.014 | 0.41 (A) | 0.39 ± 0.010 | |
| rs3354 G/A | 0.28 (A) | 0.24 ± 0.018 | 0.30 (A) | 0.25 ± 0.010 | 0.22 (A) | 0.19 ± 0.009 | |
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SD, standard deviation of the mean: Four replicates were done for each pooled sample.
