Exo-Proofreading, A Versatile SNP Scoring Technology

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

Standards for allele frequency determination. (A) Fluorescence intensity measurements obtained from samples containing known proportions of two alleles (in this case, C and T). Each sample group has N = 6 except 100% C, for which N = 2. (B) Plot of the ratios of Fam and Rox fluorescence intensity measurements against the percentage of T allele in the sample. Linear regression analysis reveals a linear relationship.

This Article

  1. Genome Res. 13: 925-931

Preprint Server