Retroposed Copies of the HMG Genes: A Window to Genome Dynamics

Table 4.

Possible Extensions to mRNA Ends

HMG gene Query mRNA ← 5′ extensions → ← 3′ extensions →
RPCs cDNA ESTs RPCs cDNA ESTs
HMGA1 NM_002131.1 19 bp (1)
HMGB1 NM_002128.2 ≤100 bp (40) 40 bp (1) ≤80 bp (several) ≤1 kb (6) 1 kb (1) ≤2 kb (several)
HMGB3 NM_005342.1 10 bp (10)
HMGN1 NM_004965.1 20–62 bp (6) 20–120 bp (several) 10–20 bp (25) ≤10 bp (several)
HMGN2 NM_005517.1 24 bp (1) ≤66 bp (several)
  • RPCs with parental gene alignments that extend beyond the known transcript start and end points indicate the existence of longer transcripts. Numbers in parentheses are the number of sequences in the sequence category that corresponds to the base pair extension. HMGB1 query sequence NM_002128.2 is an updated version of the similar sequence D53874.1 used in Table 1.

This Article

  1. Genome Res. 13: 800-812

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