Table 1.
Genomic Organization of Dystrophin Genes
| Organism | Gene length (kb) | Genome % | CDS length | CDS % | Exon number | Mean exon length | Mean intron length | Average exon length | Average intron length |
| C. elegans | 31 | 0.031 | 11,022 | 35.61 | 48 | 232.67 | 424.11 | 299.1 | 466.6 |
| D. melanogaster | 131 | 0.072 | 10,491 | 8.03 | 35 | 314.29 | 3,536.38 | 423.3 | 563.9 |
| F. rubripes | 165 | 0.040 | 10,926 | 6.63 | 82 | 133.24 | 1,900.70 | n.d. | a79.0 |
| M. musculus | 2,256 | 0.065 | 11,034 | 0.49 | 79 | 174.85 | 27,488.59 | 156.3 | 1,321.4 |
| H. sapiens | 2,155 | 0.063 | 11,055 | 0.51 | 79 | 176.57 | 27,160.21 | 152.7 | 3,413.4 |
-
Mean intron and exon lengths refer to mean values in the dystrophin gene; average lengths represent mean values on available genes. Average exon and intron lengths for Drosophila, C. elegans, mouse and human had been previously reported (Deutsch and Long 1999). All lengths are expressed in bp except for gene lengths, expressed in kb. n.d.: not determined; a: this value was derived from a modal distribution and thus it represents a moda and not a mean; intron length distribution in Fugu displays 75% of introns <425 bp (in humans 75% of introns are <2609 bp) (Aparicio et al. 2002).
