LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA

Table 1.

Performance of Aligners on the ROSETTA Dataset of 1160 Total Exons in Human and Mouse

Aligner 100% exons 90% exons 70% exons Time (sec)
DIALIGN 89 96 98 388
MUMmer 0 1 3 17
GLASS 91 97 98 154
AVID 90 95 97 19
BlastZ 94 97 98 17
LAGAN 94 97 98 48

  • Columns show the percentage of exons annotated in human that are aligned to the orthologous mouse exon over at least 70%, 90%, and 100% of their length, and the time required to align the 129 sequences.

This Article

  1. Published in Advance March 12, 2003, doi: 10.1101/gr.926603 Genome Res. 13: 721-731

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