Andrew F. Neuwald; Natarajan Kannan; Aleksandar Poleksic; Naoya Hata; Jun S. Liu

Ran's C-terminal, Basic Patch, and Nucleotide Exchange Mechanisms in Light of a Canonical Structure for Rab, Rho, Ras, and Ran GTPases

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Figure 6.

Canonical interactions between the NK.D and SA regions within the Ras, Rho, and Ran families. The perspective is as shown in Figure4 B. Representations and coloring are as described in Figure 4. (A) Human Ras-GTP (pdb code: 1QRA). (B) The Rho family human Rac1 in complex with a GTP analog (pdb code: 1MH1). (C) Canine Ran-GDP (pdb code: 1BYU).