Table 5.
Effects of Stringency of TF Sites on Specificity
| Stringency | Sensitivity | Model 1 | Model 2 |
| High | 42% | 14/15 | 4/4 |
| Medium | 61% | 2/5 | 2/5 |
| Low | 71% | 0/7 | 1/10 |
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High stringency is the original model I and II, as in the above analyses. In medium stringency, we lower the matrix cutoff scores to NF-κB, 0.95; AP1, 0.95; IK1, 0.94; STAT, 0.91; IK3, IRF1, IRF2, ISRE, 0.86. Low stringency sets the matrix cutoff scores to NF-κB, 0.92; AP1, 0.95; IK1, 0.94; STAT, 0.91; IK3, IRF1, IRF2, ISRE, 0.86. As we lower the matrix cutoffs, only the additional predictions are shown in the table.
