Computationally Identifying Novel NF-κB-Regulated Immune Genes in the Human Genome

Table 3.

Model 2 Predictions of Immune Genes Among Well Characterized Genes

Gene name Acc. no. Evidence of NF-κB regulation Immune gene Model score Functions in immune system
M-CSF-1 M37435 Promoter Study(1) +(2) 0.586 Macrophage differentiation
B factor S67310 Promoter Study(1) +(3) 0.975 MHC class III gene
MyD118 NM_015675 Promoter Study(4)Gene(5)Array(6) +(7) 0.500 Myeloid cell differentiation
Ecto-ATPase U91510 Gene(8) +(9) 0.586 T: cytokine secretion, cytolytic activity; B: Ab  secretion, proliferation
  • For table legend, please see Table 2. Ref. (1) Baeuerle and Baichwal 1997. (2) Hamilton 1997. (3) Campbell et al. 1986. (4) De Smaele et al. 2001. (5) Expression data in T:TNF, PMA (De Smaele et al. 2001). (6) Expression data in 3T3:CSF1 (Fambrough et al. 1999); B:LPS, IL1 (Li et al. 2001). (7) Vairapandi et al. 1996.(8) Expression data in NK:IL2 (Dombrowski et al. 1998); HUVEC:CMV (Kas-Deelen et al. 2001); hepatoma cells: Dioxin (Gao et al. 1998). (9) Dombrowski et al. 1998.

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  1. Genome Res. 13: 654-661

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