Table 1.
Position-Specific Amino Acid Frequencies (Expressed as a Percentage) at the Three C-Terminal Positions for Each of the Genomes Studied
| AA | M. jannaschii | E. coli | S. cerevisiae | |||||||||
| −1 | −2 | −3 | ORF | −1 | −2 | −3 | ORF | −1 | −2 | −3 | ORF | |
| A | 2.4 | 1.9 | 2.7 | 5.4 | 10.2 | 9.4 | 7.6 | 9.5 | 5.2 | 4.2 | 4.8 | 5.5 |
| C | 0.8 | 0.5 | 1.0 | 1.3 | 1.2 | 1.2 | 1.1 | 1.2 | 1.7 | 1.5 | 1.4 | 1.3 |
| D | 4.0 | 3.2 | 4.3 | 5.5 | 4.1 | 3.7 | 4.1 | 5.1 | 5.1 | 5.2 | 5.4 | 5.8 |
| E | 13.3 | 8.6 | 9.0 | 8.7 | 8.2 | 6.4 | 8.3 | 5.7 | 6.5 | 5.8 | 6.2 | 6.5 |
| F | 4.5 | 5.4 | 3.9 | 4.3 | 3.6 | 2.8 | 3.4 | 3.9 | 5.3 | 5.8 | 5.5 | 4.5 |
| G | 4.9 | 6.7 | 4.6 | 6.3 | 6.7 | 6.5 | 5.7 | 7.4 | 2.6 | 4.5 | 4.6 | 5.0 |
| H | 1.4 | 1.1 | 1.2 | 1.4 | 4.3 | 2.6 | 2.7 | 2.3 | 2.7 | 2.3 | 2.3 | 2.2 |
| I | 10.0 | 9.6 | 11.2 | 10.5 | 3.7 | 4.0 | 5.2 | 6.0 | 7.1 | 6.3 | 6.6 | 6.6 |
| K | 17.2 | 17.6 | 14.8 | 10.4 | 10.9 | 8.7 | 7.0 | 4.4 | 11.5 | 10.9 | 8.8 | 7.3 |
| L | 11.7 | 11.2 | 12.3 | 9.5 | 7.9 | 9.6 | 10.1 | 10.6 | 10.5 | 9.3 | 10.3 | 9.6 |
| M | 0.6 | 2.6 | 2.3 | 2.3 | 1.3 | 2.1 | 1.7 | 2.8 | 2.2 | 1.9 | 2.3 | 2.1 |
| N | 4.2 | 6.1 | 5.4 | 5.3 | 4.0 | 4.4 | 4.2 | 4.0 | 7.1 | 5.5 | 5.8 | 6.1 |
| P | 1.5 | 1.4 | 2.0 | 3.4 | 2.9 | 3.2 | 4.7 | 4.4 | 2.3 | 2.9 | 3.6 | 4.3 |
| Q | 3.7 | 1.9 | 1.3 | 1.4 | 6.6 | 5.4 | 4.7 | 4.4 | 4.4 | 4.0 | 4.1 | 3.9 |
| R | 5.6 | 6.5 | 6.3 | 3.8 | 8.7 | 7.5 | 7.9 | 5.5 | 4.7 | 6.5 | 4.9 | 4.5 |
| S | 3.8 | 4.6 | 5.2 | 4.5 | 6.2 | 7.0 | 5.9 | 5.8 | 6.7 | 8.7 | 8.3 | 9.0 |
| T | 1.9 | 3.2 | 2.7 | 4.0 | 1.1 | 5.3 | 4.7 | 5.4 | 3.8 | 5.3 | 4.6 | 5.9 |
| V | 2.9 | 4.2 | 5.5 | 6.8 | 4.8 | 6.3 | 6.5 | 7.1 | 5.3 | 4.6 | 5.7 | 5.6 |
| W | 1.5 | 0.8 | 0.9 | 0.7 | 1.6 | 1.1 | 1.5 | 1.5 | 1.7 | 1.0 | 1.3 | 1.0 |
| Y | 4.1 | 2.8 | 3.6 | 4.4 | 2.2 | 2.8 | 3.0 | 2.9 | 3.5 | 3.8 | 3.7 | 3.4 |
| AA | C. elegans | A. thaliana | H. sapiens | |||||||||
| −1 | −2 | −3 | ORF | −1 | −2 | −3 | ORF | −1 | −2 | −3 | ORF | |
| A | 5.2 | 4.1 | 4.8 | 6.3 | 6.2 | 4.9 | 5.5 | 6.3 | 5.3 | 6.0 | 6.4 | 7.0 |
| C | 2.7 | 2.2 | 2.0 | 2.1 | 2.6 | 2.2 | 2.0 | 1.8 | 3.2 | 2.7 | 2.4 | 2.2 |
| D | 4.3 | 4.7 | 4.6 | 5.3 | 4.5 | 4.8 | 4.9 | 5.5 | 4.5 | 5.0 | 4.4 | 4.9 |
| E | 5.7 | 5.5 | 5.4 | 6.5 | 5.1 | 5.8 | 5.1 | 6.8 | 5.1 | 6.9 | 6.8 | 7.1 |
| F | 8.5 | 5.7 | 5.7 | 4.9 | 5.7 | 5.0 | 5.0 | 4.3 | 4.6 | 3.4 | 3.8 | 3.7 |
| G | 3.0 | 4.4 | 4.2 | 5.3 | 3.7 | 5.5 | 4.9 | 6.4 | 3.7 | 6.2 | 6.1 | 6.8 |
| H | 3.4 | 2.6 | 2.2 | 2.3 | 2.6 | 2.5 | 2.4 | 2.3 | 3.5 | 2.8 | 2.7 | 2.5 |
| I | 6.4 | 6.1 | 6.3 | 6.2 | 5.4 | 5.1 | 5.1 | 5.3 | 4.5 | 3.7 | 3.6 | 4.4 |
| K | 8.8 | 10.1 | 8.7 | 6.5 | 6.2 | 7.7 | 7.1 | 6.4 | 7.5 | 7.9 | 7.2 | 5.7 |
| L | 9.3 | 8.1 | 8.7 | 8.7 | 10.2 | 8.6 | 9.9 | 9.5 | 11.1 | 8.5 | 9.2 | 9.9 |
| M | 1.9 | 2.2 | 2.1 | 2.6 | 2.1 | 2.0 | 2.1 | 2.4 | 2.1 | 1.9 | 2.1 | 2.2 |
| N | 7.4 | 6.6 | 5.1 | 4.9 | 5.1 | 4.5 | 4.2 | 4.4 | 4.0 | 3.8 | 3.3 | 3.7 |
| P | 2.6 | 3.8 | 4.6 | 4.9 | 4.2 | 4.3 | 5.0 | 4.8 | 5.6 | 6.1 | 6.2 | 6.2 |
| Q | 5.0 | 4.0 | 3.9 | 4.1 | 3.2 | 3.5 | 3.9 | 3.5 | 4.8 | 4.8 | 4.6 | 4.7 |
| R | 4.5 | 6.7 | 5.9 | 5.2 | 6.6 | 7.2 | 6.3 | 5.4 | 5.2 | 6.4 | 5.6 | 5.6 |
| S | 6.7 | 8.6 | 9.0 | 8.0 | 10.0 | 10.8 | 10.7 | 9.0 | 9.5 | 9.4 | 10.0 | 8.0 |
| T | 3.2 | 4.8 | 6.5 | 5.8 | 4.6 | 5.6 | 5.4 | 5.1 | 4.9 | 5.2 | 6.4 | 5.3 |
| V | 6.1 | 5.3 | 5.8 | 6.2 | 6.9 | 5.6 | 6.0 | 6.7 | 6.5 | 4.9 | 4.9 | 6.1 |
| W | 1.1 | 1.4 | 1.1 | 1.1 | 1.5 | 1.5 | 1.4 | 1.3 | 1.4 | 1.5 | 1.6 | 1.2 |
| Y | 4.3 | 3.1 | 3.4 | 3.2 | 3.7 | 3.1 | 3.2 | 2.9 | 3.1 | 2.8 | 2.6 | 2.7 |
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The fourth column for each organism (ORF) shows the amino acid frequencies across the entire ORF array.











