
Multiple alignment of the catalytic regions of the putative P. falciparum SP1 (PF13_0118) and the representative proteolytically active signal peptidase I using T-coffee program followed by manual correction. The catalytic dyad Ser (S175) and Lys (K274), which are part of the active sites, is highlighted with arrowheads. Graphic presentation of the alignment and the consensus sequence were obtained by the program BOXSHADE 3.21. Conserved residues are shaded with black and gray. The accession numbers of SP1 protein sequences used for alignment refer to Figure 5.











