Species-Specific Class I Gene Expansions Formed the Telomeric 1 Mb of the Mouse Major Histocompatibility Complex

Table 1.

Genes and Pseudogenes in the Mouse Telomeric Class I Region

Name Position Direction ORF Features
Class I Non class I
H2-Tw5 4,316–8,242 + H2-T, similar to X16219 and U21906
H2-Tw4ϑ 17,389–21,407 H2-T, similar to X16211
H2-Tw3 25,163–28,708 + H2-T, similar to X16209 and NM_008208
H2-Tw2ϑ 39,715–44,582 H2-T, similar to X16208
H2-Tw1ϑ 46,137–51,153 H2-T, similar to X15147
Rpp21 145,924–148,093 + Homologous to human ribonuclease P subunit, RPP21 (AF212152)
Trim39 (Rnf23) 149,120–162,262 + RING finger gene, Rnf23 (AB046382)
H2-M10.1 174,553–176,694 + H2-M10 family
H2-M10.2 214,020–216,155 + H2-M10 (AF016309)
H2-M10.3 256,236–258,381 + H2-M10 family
H2-M10.4ϑ 296,108–299,108 H2-M10 family
H2-M10.5 356,884–359,049 + H2-M10 family
H2-M7.2 429,850–432,445 + + H2-M1 family
H2-M1 likeϑ 442,912–446,564 H2-M1 family
H2-M9 525,306–527,525 + H2-M9 (NM_008205)
H2-M1 554,882–557,072 + H2-M1 (M20985)
H2-M7ϑ 585,974–588,651 H2-M7 (L14276)
H2-M8 588,936–589,638 + H2-M8 (L14277), gene fragment
H2-M10.6 613,059–616,059 + H2-M10 family
H2-M10.7 643,734–645,899 + + H-M10 family
H2-M10.8 683,235–685,369 + + H2-M10 family
Trim26 (Zfp173) 721,721–730,407 + + RING finger gene, homologous to human ZNF173 (XM_004549)
Trim15 (ZfpB7) 731,722–738,217 + RING finger gene, homologous to human ZNFB7 (U34249)
Trim10 (Herf1) 740,628–748,861 + + Hematopoiesis-specific RING finger gene (AF134811)
ZfpU 754,088–760,157 + Predicted RING-Finger gene
Trim31 (ZfpRingR) 769,287–780,722 + + RING finger gene, homologous to human TRIM31 (NM_007028)
ZfpW (Zfp412) 814,205–819,102 + + RING finger gene, homologous to human HZFw (AF238315-17)a
Ppp1r11 (Tctex5) 820,505–822,902 + Homologous to human PPP1R11 gene (NM_021959)
Tctex6 825,575–829,647 + Homologous to human ZNRD1 gene (AF024617)
Tctex4 829,819–836,835 + + Homologous to human HTEX4 gene (AF032110)
H2-M6ϑ 839,538–842,840 H2-M6 (L14280)
H2-M4ϑ 849,199–853,199 H2-M4 (L14278)
H2-M5 858,131–860,729 + H2-M5 (L14279)
Zfp57 874,239–881,843 + + KRAB box containing C2H2 type zinc finger gene (NM_009559)
Mog 881,951–894,435 + Myelin oligodendrocyte glycoprotein (Mog; AH006537)
Gabbr1 917,439–944,422 + + γ-aminobutyric acid (GABA) β receptor, 1 (AL078630)
  • Newly identified.

This Article

  1. Genome Res. 13: 589-600

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