Species-Specific Class I Gene Expansions Formed the Telomeric 1 Mb of the Mouse Major Histocompatibility Complex

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Figure 2.
Figure 2.

Alignment of the deduced amino acid sequences of two H2-T proteins and the H2-M1 family with their closest relatives. Tw5 is compared with H2-Blbc of strain 129 (accession no. NM_008199) and Tw3 with T3k of strain C3H (accession no. NM_008208). M1, M9, and M7.2 of haplotype bc are compared with M1 of the b haplotype (accession no. M20985); the purple box highlights the only allelic variation. M9 of thed haplotype (accession no. NM_008205) is identical to M9bc and not shown. The position of the highly conserved cysteine residues are marked in yellow; putative sites for N-linked glycosylation are marked in light blue; residues normally found at the ends of the peptide-binding site in Mhc class Ia molecules are listed below the sequences, with green highlights where conserved and pink where not.

This Article

  1. Genome Res. 13: 589-600

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