Table 1.
The 13 Metabolic Enzymes Which Have Homologs in All Major Taxonomic Partitions, Including Viruses
| Accession | Description | Pathway |
| P00379 | Dihydrofolate reductase (EC 1.5.1.3) | FormylTHF biosynthesis, folic acid biosynthesis |
| P00470 | Thymidylate synthase (EC2.1.1.45) | FormylTHF biosynthesis, deoxypyrimidine nucleotide/side metabolism |
| P00479 | Aspartate carbamoyltransferase catalytic chain (EC 2.1.3.2) | Pyrimidine biosynthesis |
| P00861 | Diaminopimelate decarboxylase (EC4.1.1.20) | Lysine and diaminopimelate biosynthesis |
| P04391 | Ornithine carbamoyltransferase chain I (EC2.1.3.3) | Arginine biosythesis II |
| P05459 | Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-) | Pyridoxal 5′-phosphate biosynthesis |
| P06960 | Ornithine carbamoyltransferase chain F (EC2.1.3.3) | Arginine biosynthesis II |
| P08328 | D-3-phosphoglycerate dehydrogenase (EC1.1.1.95) | Serine biosynthesis |
| P17169 | Glucosamine-fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) | Dissimilation of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminic acid, UDP-N-acetylglucosamine biosynthesis |
| P22939 | Geranyltranstransferase (EC2.5.1.10) | Polyisoprenoid biosynthesis |
| P27830 | DTDP-glucose 4,6-dehydratase (EC 4.2.1.46) | dTDP-rhamnose biosynthesis, enterobacterial common antigen biosynthesis |
| P37759 | DTDP-glucose 4,6-dehydratase (EC4.2.1.46) | dTDP-rhamnose biosynthesis, enterobacterial common antigen biosynthesis |
| P52643 | D-lactate dehydrogenase (EC1.1.1.28) | Fermentation |
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Column names: database Accession number, database Description line, both from SwissProt (Bairoch and Apweiler 2000) and the corresponding Pathway name, according to EcoCyc (Karp et al. 2000). Note that an enzyme may participate in more than one pathway (Ouzounis and Karp 2000). Table is sorted by Accession number.
