
Distribution of the 548 known E. coli metabolic enzymes into 37 taxonomic combinations (see Methods). The seven taxonomic groups correspond to domains of life in the case of Archaea and Bacteria or the four major eukaryotic groups (Fungi, Metazoa, Protista, Viridiplantae), while Viruses are considered as an additional group (see Methods). Universal enzymes are colored in gray (dark gray for those with viral homologs), those with homologs in Eucarya in blue, with homologs in Archaea in red, and in Bacteria only in green. Other combinations of the seven taxonomic groups are shown in white (see Methods).











