Table 2.
Linkage Disequilibrium Statistic (D′) in RAS Genes in Whites (Lower Triangle) and Blacks (Upper Triangle)
| 1. REN | C-4021T | C-3212T | A4280C | G5795T | C10377T | |||||
| C-4021T | — | 1.00 | 0.10 | 0.57 | 0.12 | |||||
| C-3212T | 1.00 | — | 1.0 | 0.73 | 1.0 | |||||
| A4280C | 1.00 | 1.00 | — | 0.95 | 0.57 | |||||
| G5795T | 1.00 | 1.00 | 1.00 | — | 0.02 | |||||
| C10377T | 1.00 | 1.00 | 1.00 | 1.00 | — | |||||
| 2. AGTR1 | A-777T | G-680T | A-119G | C43732T | A44221G | |||||
| A-777T | — | 1.00 | 1.00 | 0.12 | 0.10 | |||||
| G-680T | 1.00 | — | 1.00 | 0.09 | 0.10 | |||||
| A-119G | 1.00 | 1.00 | — | 0.08 | 0.10 | |||||
| C43732T | 0.13 | 0.03 | 0.10 | — | 1.00 | |||||
| A44221G | 1.00 | 1.00 | 1.00 | 1.00 | — | |||||
| 3. AGT | C-532T | A-217G | A-6G | C3889T | C4072T | |||||
| C-532T | — | 1.00 | 1.00 | 1.00 | 1.00 | |||||
| A-217G | 1.00 | — | 1.00 | 1.00 | 1.00 | |||||
| A-6G | 1.00 | 1.00 | — | 1.00 | 1.00 | |||||
| C3889T | 1.00 | 1.00 | 1.00 | — | 0.93 | |||||
| C4072T | 0.87 | 0.87 | 0.96 | 1.00 | — | |||||
| 4. ACE | A-239T | A7941G | C8342T | A10593G | A11599G | A12292G | A15990G | C17911T | C19329T | A20060G |
| A-239T | — | 0.42 | 0.30 | 0.26 | 0.24 | 0.29 | 0.27 | 0.33 | 0.19 | 0.33 |
| A7941G | 0.50 | — | 0.80 | 1.00 | 1.00 | 1.00 | 0.93 | 0.79 | 0.72 | 0.76 |
| C8342T | 0.96 | 0.43 | — | 1.00 | 0.96 | 0.95 | 0.95 | 0.81 | 0.62 | 0.70 |
| A10593G | 0.98 | 0.41 | 0.99 | — | 1.00 | 1.00 | 1.00 | 0.98 | 0.83 | 1.00 |
| A11599G | 0.94 | 0.27 | 0.97 | 0.99 | — | 0.96 | 0.96 | 0.96 | 0.81 | 0.98 |
| A12292G | 0.98 | 0.44 | 0.99 | 1.00 | 0.99 | — | 0.96 | 0.82 | 0.62 | 0.71 |
| A15990G | 0.96 | 0.42 | 0.99 | 0.99 | 0.97 | 1.00 | — | 1.00 | 0.74 | 0.89 |
| C17911T | 0.98 | 0.44 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | — | 0.85 | 0.88 |
| C19329T | 0.92 | 0.42 | 0.99 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | — | 0.82 |
| A20060G | 0.96 | 0.44 | 0.97 | 0.99 | 0.97 | 0.99 | 1.00 | 1.00 | 1.00 | — |
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Shaded area indicates statistical significance (p < 0.0001) after adjusting for multiple tests.
