Figure 5.
Evolutionary analysis of duplicated ZNF genes. Conceptual translation of ZNF33 orthologs aligned with ZNF33A andZNF33B. Differences to hZNF33A are highlighted in grey. Putative base-contacting residues of each zinc finger (positions −1, 2, 3, and 6 relative to the start of the α helix) are indicated below the alignment. The core residues of each zinc finger are in bold. TheZNF33 genes were originally defined by two incomplete cDNAs,ZNF11 and ZNF33, before their duplicated status was known (Thiesen 1990). ZNF33A andZNF33B have been previously defined as ZNF11/33A andZNF11/33B for this reason (Jackson et al 1996; 1999).
