Genomic Sequence and Transcriptional Profile of the Boundary Between Pericentromeric Satellites and Genes on Human Chromosome Arm 10p

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Figure 4.
Figure 4.

Genomic origin of human paralogs of the 10q11 sequence. Each independent BLAST hit greater than 5 kb in length within the EMBL-NR database is shown. Regions of high identity to the Repeatmasked 10p11 sequence are indicated by black lines. The % identity to the 10p11 sequence, the accession number, and the position within the current human draft (where known) are also indicated. The appropriate portion of the 10p11 summary map (Fig. 2C) is shown for reference, together with the identity of specific repeats (Table 3). (A) Paralogs of contig 1. (B) Paralogs of proximal ∼200 kb of contig 2. (C) Maximum likelihood analysis of Capicuapseudogenes from Fig. 4B, constructed using a 3293bp alignment spanning nucleotides 74113–77345bp of contig 2. All nodes have >90% bootstrap support with the exception of the three nodes marked with an asterisk. For details of tree construction see Methods. (D). Paralogs of distal 900 kb of contig 2.

This Article

  1. Genome Res. 13: 159-172

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