The most common transcription factor domains in tissue-enriched SASs. The SASs were inspected for tissue specificity using the library of origin of their EST components. An SAS was considered tissue-enriched when it contained at least three ESTs found exclusively in a given library. The SASs were translated using the ESTScan algorithm. Domain occurrence was revealed by querying the Pfam database with the corresponding amino acid sequences using the default settings of Pfam 7.0 [“global and local alignments merged” and “Pfam gathering threshold (GA)”]. The 10 most frequent transcription factor domains were determined (see Fig. 6) and inspected for tissue specificity. (A) The most represented transcription factor domains among the tissue-enriched SASs along with the number of SASs in each of them. (B) The same data as in A showing the tissue origin and number of occurrences.
