Millions of Years of Evolution Preserved: A Comprehensive Catalog of the Processed Pseudogenes in the Human Genome

Table 1.

Number of Pseudogenes on Each Chromosome






Processed ψG



Chr.
Chr. length (Mb)
Chr. GC content
Ensembl genes total (known)
True (RP)
Putative
Disrupted
Frag. ψG
Dup. ψG
ψG density (per Mb)
1 247 0.41 2330 (1855) 709 (184) 65 103 521 262 2.87
2 241 0.40 1588 (1177) 527 (131) 57 76 432 168 2.19
3 195 0.39 1236 (949) 473 (113) 40 65 442 203 2.43
4 192 0.37 908 (685) 351 (75) 24 48 315 132 1.83
5 181 0.39 1046 (809) 433 (99) 47 55 338 110 2.39
6 170 0.39 1180 (1003) 502 (130) 29 66 276 116 2.95
7 157 0.40 1140 (848) 448 (81) 52 66 391 173 2.85
8 144 0.39 789 (605) 340 (91) 22 44 285 85 2.36
9 132 0.41 895 (688) 331 (66) 22 48 241 87 2.51
10 134 0.41 914 (682) 307 (86) 18 40 285 115 2.29
11 137 0.41 1372 (1064) 445 (79) 58 62 356 211 3.25
12 131 0.40 1143 (887) 409 (110) 45 55 363 168 3.12
13 113 0.38 398 (300) 236 (37) 17 29 141 56 2.09
14 104 0.41 737 (573) 286 (74) 40 36 198 69 2.75
15 99 0.42 750 (537) 242 (43) 14 44 180 109 2.44
16 82 0.44 1025 (798) 249 (41) 29 54 343 163 3.04
17 80 0.45 1220 (961) 246 (70) 38 46 263 189 3.08
18 78 0.39 318 (244) 144 (40) 16 24 156 76 1.85
19 60 0.47 1464 (1218) 222 (63) 32 81 324 163 3.70
20 63 0.44 641 (593) 149 (39) 7 8 83 28 2.37
21 45 0.41 230 (204) 88 (20) 2 8 44 17 1.96
22 48 0.48 571 (469) 133 (24) 21 21 115 73 2.77
X 149 0.39 901 (717) 432 (59) 37 89 304 125 2.90
Y 58 0.39 124 (82) 117 (1) 5 23 135 117 2.02
Total
3040
0.41
22920 (17948)
7819 (1756)
737
1191
6531
3015
2.57
  • (Ensembl genes) Functional human genes annotated by Ensembl (Release 8.30a 1), which include known genes and novel genes. (Processed ψG) Processed pseudogenes. Definition of the “true,” “putative,” and “disrupted” processed pseudogenes are described in the text. The numbers of ribosomal protein processed pseudogenes are included in brackets. (Frag. ψG) Pseudogenic fragments. (Dup. ψG) Duplicated pseudogene. (ψG density) Average number of processed pseudogenes per 1 Mb DNA; only “true” processed pseudogenes are included.

This Article

  1. Genome Res. 13: 2541-2558

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