Table 1.
Definition of Variables and Nominal Values for Signaling Proteins at Steady State
|
Dependent variables |
Acronym |
Symbol |
Concentration [μM] |
Independent variables |
[μMsec−1]/[sec−1] |
|---|---|---|---|---|---|
| TNF Necrosis Factor | TNF | m1 | 20 | — | — |
| TNF Receptor 1 | TNFR1 | m2 | 25 | k2f/k2r | 0.139/0.00556 |
| TNFR1-complex | — | m3 | 0 | — | — |
| TNFR1-associated death domain protein | TRADD | m4 | 25 | k4f/k4r | 0.139/0.00556 |
| TRADD-complex | — | m5 | 0 | — | — |
| Fas-associated death domain | FADD | m6 | 0 | k6f/k6r | 0.139/0.00556 |
| FADD-complex | — | m9 | 0 | — | — |
| Receptor-interacting protein | RIP | m7 | 25 | k7f/k7r | 0.139/0.00556 |
| RIP-complex | — | m10 | 0 | — | — |
| TNF-Receptor-associated factor 2 | TRAF2 | m8 | 12 | k8f/k8r | 0.139/0.00556 |
| TRAF2-complex | — | m11 | 0 | — | — |
| IκB kinase | IKK | m9 | 25 | k9f/k9r | 0.139/0.00556 |
| NF-κB Inhibitor/Nuclear factor κB | IkB/NF-κB | m14 | 25 | k14f/k14r | 0.139/0.00556 |
| IKK-complex | — | m12 | 0 | — | — |
| NF-κB Inhibitor | IκB | m16 | 0 | — | — |
| Nuclear factor κB
|
NK-κB
|
m17
|
0
|
—
|
—
|
