A Biophysical Approach to Transcription Factor Binding Site Discovery

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Figure 9
Figure 9

Comparison of the false-negative fraction versus the number of candidate sites found within the non-ORF fraction of the E. coli K12 genome for the information-based weight matrix (blue) and QPMEME (red) methods. Both CRP site searches are based on the same set of example sites (Robison et al. 1998) and tested against entries in RegulonDB. (⋄) The point corresponding to the QPMEME-derived threshold. The (+) low and (*) high thresholds used in Robison et al. (1998).

This Article

  1. Genome Res. 13: 2381-2390

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