Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

Table 1.

Posttranslational Modifications


Type of modification

Number of modifications

Number of proteins
Acetylation 37 16
ADP ribosylation 6 4
Alkylation 4 3
Amidation 8 2
Carboxylation 45 6
Disulphide bridge 136 41
Glycation 33 11
Glycosylation 191 54
GPI anchor 7 6
Hydroxylation 7 2
Methylation 47 23
Myristoylation 12 11
Neddylation 1 1
Nitration 6 2
Palmitoylation 33 19
Phosphorylation 1104 305
Prenylation 12 10
Proteolytic cleavage 146 71
S-Nitrosylation 4 4
Sulfation 23 8
Sumoylation 16 11
Transglutamination 5 2
Ubiquitination
17
8
  • The number of sites annotated by various posttranslation modifications is shown.

This Article

  1. Genome Res. 13: 2363-2371

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