Representational Oligonucleotide Microarray Analysis: A High-Resolution Method to Detect Genome Copy Number Variation

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Figure 4
Figure 4

The mean segmentation calculated from the analysis of SK-BR-3 compared with (A,B) the normal reference and (C,D) CHTN159. In all panels, the Y-axis is the value of the mean segment for each probe in log scale. In A and C, the X-axis (Mean Segment Index) is in ascending value of the assigned mean segment. In B and D, the X-axis (Gen Index) is the genomic index, as described above. Plotted on top of the mean segment data is a copy number lattice extrapolated from the array data using formulas within the text (horizontal lines). The calculated copy number for each horizontal line is to the right of the lattice.

This Article

  1. Genome Res. 13: 2291-2305

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