Table 1.
Gene Categorization
|
Gene/domain category |
No. of genes |
|---|---|
| 7 Transmembrane domain receptors | 9 |
| Acyltransferases | 4 |
| Alcohol dehydrogenases | 16 |
| Amino oxidases | 3 |
| AMP binding proteins | 3 |
| C1q domain receptors | 10 |
| Cadherins | 8 |
| Carbonic anhydrases | 3 |
| Carboxylesterases | 3 |
| Carboxypeptidases | 4 |
| Claudins | 7 |
| Collagens | 5 |
| CUB/Sushi domain receptors | 12 |
| Cystatins | 1 |
| Cytochromes | 5 |
| Cytokines and chemokines | 7 |
| Epidermal growth factor receptors | 12 |
| Epidermal growth factors | 10 |
| Fibrinogens | 11 |
| Fibroblast growth factors | 6 |
| Fibronectins | 12 |
| Glypicans | 2 |
| Hormones | 2 |
| Integrins | 2 |
| Interferons | 2 |
| Laminins | 3 |
| Lectins | 14 |
| Leucine-rich repeat receptors | 51 |
| Lipocalins | 3 |
| Low-density lipoprotein receptors | 5 |
| Membrane channels | 11 |
| Olfactomedins | 5 |
| Peptidases | 16 |
| Phosphodiesterases | 3 |
| Proteases and protease inhibitors | 14 |
| Scavenger receptor domain proteins | 2 |
| Semaphorins and plexin repeat receptors | 9 |
| Thrombospondins and ADAMs | 11 |
| Transforming growth factors | 2 |
| Trypsins and trypsin inhibitors | 17 |
| Tumor necrosis factor receptors | 10 |
| Tumor necrosis factors | 4 |
| Tyrosine kinase receptors | 1 |
| Uteroglobins | 1 |
| WNT and WNT induced signaling proteins | 5 |
| Other immunoglobulin superfamily | 64 |
| Other secreted proteins | 217 |
| Other transmembrane proteins | 252 |
| Total number of secreted and transmembrane proteins | 879 |
| Galactosyltransferases | 6 |
| Glycosyltransferases | 11 |
| Kinases | 1 |
| Mitochondrial carrier proteins | 3 |
| Sulfatases | 4 |
| Sulfotransferases | 3 |
| Thioredoxins | 7 |
| Transcription factors | 8 |
| Other cytoplasmic and nuclear | 93 |
| Total number of cytoplasmic and nuclear proteins | 136 |
| Total number of proteins with unpredicted localization | 6 |
| Total number of SPDI genes
|
1021
|
-
Gene families and categories as determined by computational assessment of protein domains and sub-cellular localization, as well as curation.
