Pericentromeric Duplications in the Laboratory Mouse

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Figure 3.
Figure 3.

Consensus sequences of novel mouse satellites. (A) Consensus sequence of the 27-bp satellite derived by MEME analysis of sequence flanking dpE on MMU1. The consensus represents 83 monomers, each 27 bp in length and occurring in a tandem, head-to-tail fashion within BAC RP23–104K20. The information content (in bits) is included to indicate the degree of conservation at each position in the consensus. The base with the greatest probability of occurrence at each position is shown in the first line of the multilevel consensus sequence; alternative bases are indicated on the second line only if they occur with a probability greater than 0.2. (B) Consensus sequence of the 36-bp satellite derived by MEME analysis of sequence within dpA. The consensus represents 106 monomers, each 36 bp in length, derived from several genomic locations: 62 monomers from MMU5, 40 from MMU6, and four from MMU8. Monomers of this 36-bp satellite are arranged in a tandem, head-to-tail orientation.

This Article

  1. Genome Res. 13: 55-63

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