Genome Rearrangements in Mammalian Evolution: Lessons From Human and Mouse Genomes

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Figure 2.
Figure 2.

X-chromosome: from local similarities, to synteny blocks, to breakpoint graph, to rearrangement scenario. (a) Dot-plot of anchors. Anchors are enlarged for visibility. (b) Clusters of anchors. (c) Rectified clusters. (d) Synteny blocks. (e) Synteny blocks (symbolic representation as genome rearrangement units). (f) 2D breakpoint graph superimposed on synteny blocks. The projections of the 2D graph onto the human and mouse axes form the conventional breakpoint graphs. (g) 2D breakpoint graph. The four cycles in the breakpoint graph are shown by different colors. (h) A most parsimonious rearrangement scenario for human and mouse X-chromosomes.

This Article

  1. Published in Advance December 30, 2002, doi: 10.1101/gr.757503 Genome Res. 13: 37-45

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