Figure 1.
Pairwise comparison using TBLASTX of the human and mouse genomic sequences coding for the HLA class II alpha chain. Black boxes indicate the coding exons, while black diagonals indicate the conserved alignments. The score of the conserved alignments (divided by 10) is given in the lower panels. Although conserved regions between the human and mouse genomic sequences coding for these genes fully include the coding exons, a substantial fraction of intronic regions is also conserved. The TBLASTX outptut was post-processed to show a continuous non-overlapping alignment.
