Table 2.
Gene Ontology Functional Classification
| GO functional classification | Number of human orthologs | Number in intermediate paralog set | Number in close paralog set |
| Total for which classification was possible | 2525 | 49 | 94 |
| Anticoagulant | 2 | 0 | 0 |
| Antioxidant | 1 | 0 | 0 |
| Apoptosis regulator | 20 | 1 | 1 |
| Cell adhesion molecule | 133 | 2 | 5 |
| Cell cycle regulator | 38 | 1 | 3 |
| Chaperone | 160 | 1 | 5 |
| Chaperone regulator | 17 | 0 | 2 |
| Defense/immunity protein | 76 | 1 | 4 |
| Enzyme | 1395 | 29 | 56 |
| Enzyme regulator | 107 | 1 | 6 |
| Ligand binding or carrier | 1121 | 25 | 38 |
| Lysine | 10 | 0 | 0 |
| Molecular function unknown | 113 | 1 | 4 |
| Motor | 33 | 1 | 1 |
| Nucleic acid binding | 595 | 17 | 32 (0.02) |
| Obsolete | 88 | 0 | 4 |
| Protein stabilization | 1 | 0 | 0 |
| Protein tagging | 1 | 0 | 1 |
| Signal transducer | 992 | 14 | 39 |
| Storage protein | 2 | 0 | 0 |
| Structural protein | 168 | 3 | 6 |
| Toxin | 9 | 0 | 0 |
| Transporter | 486 | 8 | 15 |
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↵ P values have been calculated from a two-tailed Fisher's exact test and are shown for values <0.05. Correction for multiple tests has not been performed.
