Comparative Genomic Sequence Analysis of the Human Chromosome 21 Down Syndrome Critical Region

Table 4.

Conserved Sequences (CSs) between the Human DSCR and the Corresponding Mouse Region

Total No. of CSs No. of CSs matched with known exons No. of exons matched with CSs (out of 123 known exons)
50 bp
 75% ID 1058 (113,607 bp) 178 (31,159 bp) 110
 80% ID 674 (74,892 bp) 161 (26,751 bp) 109
 85% ID 341 (39,592 bp) 132 (19,574 bp) 89
75 bp
 75% ID 526 (88,088 bp) 138 (30,983 bp) 104
 80% ID 353 (59,173 bp) 123 (26,132 bp) 95
 85% ID 217 (35,794 bp) 104 (19,529 bp) 84
100 bp
 75% ID 408 (86,136 bp) 128 (32,762 bp) 103
 80% ID 254 (53,428 bp) 110 (25,773 bp) 90
 85% ID 156 (31,809 bp) 84 (18,624 bp) 73
  • Numbers in parentheses indicate total nucleotide length of CSs. The data was obtained from the analysis using the VISTA program.

  • One exon matched with more than two non-overlapping CSs.

This Article

  1. Genome Res. 12: 1323-1332

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