Comparative Genomic Sequence Analysis of the Human Chromosome 21 Down Syndrome Critical Region

Table 3.

Distribution of Repetitive Elements in the Human DSCR and the Corresponding Mouse Region

Human (1,792,995 bp) GC level 42.43% Mouse (1,350,235 bp) GC level 45.35%
number of elements percentage of sequence number of elements percentage of sequence
SINEs 982 12.97 799 8.53
 Alus 719 10.81
 B1s 273 2.36
 B2–B4 465 5.75
 IDs 26 0.13
 MIRs 263 2.16 35 0.30
LINEs 485 16.07 197 5.35
 LINE1 316 13.34 176 5.13
 LINE2 159 2.60 20 0.22
 L3/CR1 10 0.13 1 0.00
LTR elements 327 7.83 353 8.14
 MaLRs 198 4.19 269 5.46
 ERVL 58 1.19 15 0.27
 ERV_classI 54 2.10 7 0.10
 ERV_classII 3 0.11 13 1.04
DNA elements 224 3.16 67 0.81
 MER1_type 145 1.99 40 0.45
 MER2_type 33 0.78 22 0.32
Unclassified 1 0.03 8 0.18
Total interspersed repeats 40.07 23.00
Small RNA 7 0.05 11 0.07
Simple repeats 243 0.98 694 3.96
Low complexity 200 0.57 156 0.80
Total 41.63 27.79

This Article

  1. Genome Res. 12: 1323-1332

Preprint Server