Computational Identification of Operons in Microbial Genomes

Table 1.

Summary of Results for 42 Organisms

Species No. of predicted operons Genome size (Mb) No. of enzymes in operons/No. of total enzymes Ratio of enzymes of operons Average length of operons Number of operons in a shuffled genome P-value
E. coli 124 4.7 374/562 0.66 3.0 22 0.001
H. influenzae 52 1.8 160/293 0.54 3.1 11 0.006
X. fastidiosa 42 2.7 148/365 0.39 3.5 5 0.005
V. cholerae 80 4.0 237/562 0.42 3.0 11 0.001
P. aeruginosa 101 6.4 290/715 0.41 2.9 14 0.002
Buchnera sp APS 30 0.7 122/224 0.54 4.1 8 0.02
P. multocida 57 2.3 169/418 0.40 3.0 12 0.004
N. meningitidis B 38 2.3 134/404 0.33 3.5 8 0.007
H. pylori 25 1.7 81/280 0.29 3.2 6 0.02
C. jejuni 33 1.7 112/335 0.33 3.4 8 0.009
R. prowazekii 25 1.1 71/182 0.39 2.8 6 0.007
M. lot̂i 88 7.1 260/729 0.36 3.0 8 0.003
C. crescentus 48 4.1 135/372 0.36 2.8 5 0.004
B. subtilis 105 4.3 323/510 0.63 3.1 13 0.001
B. halodurans 98 4.3 308/563 0.55 3.1 13 0.001
M. genitalium 13 0.6 40/86 0.47 3.1 5 0.10
M. pneumoniae 17 0.8 50/117 0.43 2.9 6 0.03
M. pulmonis 19 1.0 60/116 0.52 3.2 4 0.01
U. urealyticum 11 0.8 33/101 0.33 3.0 3 0.04
L. lactis 62 2.4 203/367 0.55 3.3 9 0.002
S. pyogenes 46 1.9 152/283 0.54 3.3 10 0.001
S. aureus Mu50 6 2.9 21/43 0.49 3.5 0 0.005
M. tuberculosis 89 4.5 266/591 0.45 3.0 16 0.003
M. leprae 47 3.3 134/326 0.41 2.9 4 0.002
C. trachomatis 27 1.0 81/187 0.43 3.0 5 0.007
C. pneumoniae 24 1.2 75/190 0.39 3.1 4 0.007
B. burgdorferi 20 1.5 50/138 0.36 2.5 2 0.001
T. pallidum 15 1.2 44/152 0.29 2.9 5 0.03
Synechocystis 24 3.6 59/453 0.13 2.5 8 0.02
D. radiodurans 46 2.7 136/434 0.31 3.0 7 0.002
A. aeolicus 31 1.6 90/387 0.23 2.9 10 0.01
T. maritima 42 1.9 172/368 0.47 4.1 7 0.005
M. jannaschii 28 1.7 96/274 0.35 3.4 9 0.01
M. thermoautotrophicum 46 1.8 164/349 0.47 3.6 10 0.006
A. fulgidus 59 2.2 178/406 0.44 3.0 13 0.003
T. acidophilum 34 1.6 107/271 0.39 3.2 8 0.03
T. volcanium 35 1.6 116/277 0.42 3.3 7 0.006
P. horikoshii 23 1.8 80/231 0.35 3.5 4 0.01
P. abyssi 30 1.8 125/280 0.45 4.2 6 0.009
A. pernix 33 1.7 95/274 0.37 2.9 4 0.004
S. solfataricus 59 3.0 190/458 0.41 3.2 11 0.007
S. cerevisiae 33 13 74/692 0.11 2.2 16 0.047
  • The total number of enzymes that are involved in the metabolic pathways.

This Article

  1. Genome Res. 12: 1221-1230

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