Table 3.
Transcription Factor Binding Sites in the 4-kb Upstream Sequence of Clustered Genes
| CIRBP (11) | DBPA (8) | HNRPDL (13) | PABPC4 (18) | SRP75 (41) | U2AF65 (20) |
| AML-1a | AML-1a | AML-1a | AML-1a | AML-1a | AML-1a |
| δEF1 | δEF1 | δEF1 | δEF1 | δEF1 | δEF1 |
| GATA-1 | GATA-1 | GATA-1 | GATA-1 | GATA-1 | GATA-1 |
| GATA-2 | GATA-2 | GATA-2 | GATA-2 | GATA-2 | GATA-2 |
| GATA-3 | GATA-3 | GATA-3 | GATA-3 | GATA-3 | GATA-3 |
| Ik-2 | Ik-2 | Ik-2 | Ik-2 | Ik-2 | Ik-2 |
| Lyf-1 | Lyf-1 | Lyf-1 | Lyf-1 | Lyf-1 | Lyf-1 |
| MZF1 | MZF1 | MZF1 | MZF1 | MZF1 | MZF1 |
| Nkx-2.5 | Nkx-2.5 | Nkx-2.5 | Nkx-2.5 | Nkx-2.5 | Nkx-2.5 |
| SRY | SRY | SRY | SRY | SRY | SRY |
| CdxA | CdxA | CdxA | CdxA | CdxA | CdxA |
| AP-1 | AP-1 | AP-1 | AP-1 | AP-1 | |
| c-Ets-1 | c-Ets-1 | c-Ets-1 | c-Ets-1 | c-Ets-1 | |
| Oct-1 | Oct-1 | Oct-1 | Oct-1 | Oct-1 | |
| USF | USF | USF | USF | ||
| HNF-3b | HNF-3b | HNF-3b | |||
| S8 | S8 | S8 | |||
| C/EBPb1 | C/EBPb1 | C/EBPb1 | |||
| C/EBP | C/EBP | ||||
| CRE-BP | CRE-BP | ||||
| HFH-2 | HFH-2 | ||||
| HSF2 | HSF2 | ||||
| STATx | STATx | ||||
| Sp1 | Sp1 | ||||
| CREB | |||||
| GATA-X | |||||
| NF-κB | |||||
| p300 | |||||
| Pbx-1 | |||||
| Sox-5 | |||||
| CDP |
-
The top row displays the positive clones selected for synexpression studies. Numbers in parenthesis refer to the number of genes that have similar expression patterns to the corresponding gene in 14 breast cell lines as determined using Gene Spring software (see Results). Binding sites for transcription factors present in the 4-kb upstream region of all the members of a cluster group are represented in each column.
