Domains Occurring in Proteins Whose Locale Predictions by Domain Projection and Meta-A Differed
| Domain | Q Example | L | Pr(L) | Meta-A |
| ArfGAP | GLO3_YEAST | Cyt | 1.00 | Nuc |
| ARM | PLAK_XENLA | Nuc | 0.99 | Cyt |
| BPI1 | CETP_RABIT | Nuc | 0.99 | Sec |
| DnaJ | YRY1_CAEEL | Nuc | 0.87 | Sec |
| DYNc | MX1_MOUSE | Cyt | 1.00 | Nuc |
| Efhand | FCA4_TRYBB | Cyt | 1.00 | Sec |
| EXOIII | YWO2_CAEEL | Nuc | 0.76 | Sec |
| FA58C | DISA_DICDI | Sec | 0.99 | Sec |
| HX | ALB2_PEA | Sec | 0.99 | Cyt |
| IPT | REL_MOUSE | Sec | 0.88 | Nuc |
| KISc | KIP1_YEAST | Cyt | 1.00 | Nuc |
| LH2 | LOXA_LYCES | Sec | 0.97 | Cyt |
| LIM | LI11_CAEEL | Cyt | 0.98 | Nuc |
| LysM | KTXA_KLULA | Cyt | 0.67 | Sec |
| MATH | TRA1_HUMAN | Nuc | 0.99 | Cyt |
| PAS | ARNT_MOUSE | Cyt | 1.00 | Nuc |
| PDZ | SPA1_MOUSE | Cyt | 0.99 | Nuc |
| Phosphatase | MCE1_MOUSE | Cyt | 0.89 | Nuc |
| PI3Kc | PIK1_YEAST | Cyt | 0.98 | Nuc |
| PLAc | PLB1_YEAST | Cyt | 1.00 | Sec |
| PP2Ac | PP11_SCHPO | Cyt | 1.00 | Nuc |
| Protein Kinase | CC2_HUMAN | Cyt | 0.94 | Nuc |
| SH2 | STA1_MOUSE | Cyt | 1.00 | Nuc |
| SH3 | MIA_BOVIN | Cyt | 1.00 | Sec |
| TGc | TGLD_RAT | Cyt | 0.91 | Sec |
| TIR | MY88_MOUSE | Sec | 0.90 | Cyt |
| TSPc | IRBP_BOVIN | Cyt | 0.94 | Sec |
| VWA | KU88_MOUSE | Sec | 1.00 | Nuc |
| ZnF_C2HC | CNBP_HUMAN | Nuc | 0.91 | Cyt |
| ZnF_C2HC | GRP2_NICSY | Nuc | 1.00 | Sec |
| ZnF_ZZ | RF2P_DROME | Cyt | 1.00 | Nuc |
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↵Meta-A wrongly predicts a nuclear localization for ArfGap zinc finger domains on the basis that all zinc fingers bind DNA.
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↵Meta-A predicts a nuclear localization for centrosomal proteins. However, the centrosome is a nucleus-associated structure, rather than being a region of the nucleus.
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↵The signal peptide predicted in SwissProt for YWO2_CAEEL is unlikely, as it is not predicted using other methods.
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↵Predicted as secreted by Meta-A on the basis that it was originally described as a cell-wall structural protein. The six proteins mentioned in the text that have multiple locales and were predicted to have different locales by the domain projection and Meta-A methods are: SCD1_SCHPO, YB54_XENLA, YB56_XENLA, NUMB_DROME, RANG_YEAST, and SNF4_YEAST.
