Shannon Information Theoretic Computation of Synonymous Codon Usage Biases in Coding Regions of Human and Mouse Genomes

Table 4.

Pooled Synonymous Codon Frequencies for 10862 Human RefSeqs Normalized by Amino Acid Totals

Amino acid Codon number
1 2 3 4 5 6
PHE 0.465 0.535
LEU 0.132 0.191 0.072 0.397 0.078 0.130
ILE 0.364 0.473 0.162
MET 1.000
VAL 0.182 0.236 0.118 0.464
SER 0.185 0.215 0.149 0.056 0.154 0.240
PRO 0.288 0.321 0.278 0.113
THR 0.247 0.353 0.283 0.117
ALA 0.266 0.399 0.230 0.104
TYR 0.445 0.555
HIS 0.421 0.579
GLN 0.265 0.735
ASN 0.472 0.528
LYS 0.432 0.568
ASP 0.471 0.529
GLU 0.431 0.569
CYS 0.456 0.544
TRP 1.000
ARG 0.084 0.188 0.014 0.206 0.208 0.201
GLY 0.165 0.340 0.253 0.242

This Article

  1. Genome Res. 12: 944-955

Preprint Server



Current Issue

  1. January 2026, 36 (1)
  1. Current Issue
  1. Alert me to new issues of Genome Research