Comparison of the Small Molecule Metabolic Enzymes of Escherichia coli and Saccharomyces cerevisiae

Table 8.

Interactions between Different Enzymes within the Same Pathway

Consecutive enzymes (3 pairs):
Glycoprotein biosynthesis:
RHK1 (putative Dol-P-Man dependent alpha(1-3) mannosyltransferase ⇔ oligosaccharyl transferase glycoprotein complex
Pyrimidine metabolism:
UPRTase ⇔ Uridine kinase
Oxidative phosphorylation:
ATP synthase subunit h ⇔ COX5B (Cytochrome-c oxidase chain Vb)
1 enzymatic step apart (3 pairs):
Glycoprotein biosynthesis:
dolichol-P-glucose synthetase ⇔ ... ⇔ components of oligosaccharyl transferase glycoprotein complex
Pyruvate metabolism:
carbon-catabolite sensitive malate synthease ⇔ ... ⇔ pyruvate carboxylase isozymes
Oxidative phosphorylation:
ATP synthase subunit h ⇔ ... ⇔ Ubiquinol cytochrome-c reductase subunit 8
2 enzymatic steps apart (1 pair):
Starch and sucrose metabolism:
Hexokinase B ⇔ ... ⇔ ... ⇔ multifunctional trehalose-6-phosphate synthase/phosphatase complex

This Article

  1. Genome Res. 12: 916-929

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