Comparative Sequence Analysis of the X-Inactivation Center Region in Mouse, Human, and Bovine

Table 1.

Frequency of the major classes of interspersed repeated elements (in term of percent of the sequence length) in the autosomes, the X chromosome, in the Xic region taken as a whole and in introns of genes located in the Xic region

Length (kb analyzed) LINE (%) SINE (%) LTR (%) DNA (%) Total (%)
Mouse Autosomes 223,057 10.5 9.4 6.9 0.5 27.4
X chromosome 10,000 16.2 9.1 6.5 0.7 32.6
Xic region 714 14.5 14.5 8.5 0.3 37.9
Xistintrons 9 0.0 10.2 0.0 0.0 10.2
Other introns 190 17.2 13.2 3.1 0.4 33.9
Human Autosomes 348,845 17.0 14.3 6.8 2.4 40.6
X chromosome 56,667 30.2 9.6 9.0 2.5 51.2
XIC region 2300 38.9 8.4 8.6 1.3 57.2
XIST introns 18 8.2 8.9 0.5 1.0 18.6
Other introns 352 47.5 7.8 9.0 2.0 66.3
Bovine XIC region 233 46.5 9.3 1.3 0.8 57.9
XIST introns 17 17.8 5.8 0.6 0.0 24.2
  • Sequences extracted from GenBank release 124 (June 2001).

  • Data from Bailey et al. (2000).

  • Introns of protein-coding genes located in Xic region.

This Article

  1. Genome Res. 12: 894-908

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