Multiplex Three-Dimensional Brain Gene Expression Mapping in a Mouse Model of Parkinson's Disease

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

Voxelation scheme. The slices are labeled A through J, from anterior to posterior. Slice A corresponds to section 8 (6.94 mm interaural, 3.14 mm bregma) of the Mouse Brain Library (Rosen et al. 2000; Williams 2000; http://www.nervenet.org/MBL/mbl.html), slice B to section 11 (5.78 mm interaural, 1.98 mm bregma), slice C to section 12 (5.50 mm interaural, 1.70 mm bregma), slice D to section 14 (4.39 mm interaural, 0.74 mm bregma), slice E to section 16 (3.80 mm interaural, 0.00 mm bregma), slice F to section 17 (2.98 mm interaural, −0.82 mm bregma), slice G to section 20 (1.68 mm interaural, −2.12 mm bregma), slice H to section 24 (0.00 mm interaural, −3.80 mm bregma), slice I to section 28 (−1.31 mm interaural, −5.09 mm bregma), slice J to section 32 (−2.44 mm interaural, −6.24 mm bregma). The anterior–posterior coordinates of the Mouse Brain Library (interaural and bregma relative distances) are as described (Franklin and Paxinos 1997). Odd-numbered voxels (e.g., A1, A3, B1) are from the right side of the brain, and even-numbered voxels (e.g., A2, A4, B2) are from the left.

This Article

  1. Genome Res. 12: 868-884

Preprint Server