Fourfold Faster Rate of Genome Rearrangement in Nematodes Than in Drosophila

Table 2.

Association of Translocation and Transposition Breakpoints with Particular Repeats

Dispersed repeat All 16,574 spacers Translocation breakpoints P-value for translocations Transposition breakpoints P-value for transpositions
CeRep10 582 23 1.00 25 1.00
CeRep11 137 4 1.00 7 1.00
CeRep12 553 17 1.00 24 1.00
CeRep13 354 22 0.003 15 1.00
CeRep14 320 16 0.44 11 1.00
CeRep15 186 14 0.005 10 1.00
CeRep17 345 19 0.06 11 1.00
CeRep18 197 10 1.00 11 0.90
CeRep19 685 33 0.02 18 1.00
CeRep20 144 9 0.47 11 0.045
CeRep21 177 8 1.00 11 0.36
CeRep22 122 6 1.00 8 0.75
CeRep23 708 27 1.00 31 0.42
CeRep24 625 20 1.00 23 1.00
CeRep25 7 1 1.00 0 1.00
CeRep26 154 4 1.00 7 1.00
CeRep27 71 5 1.00 4 1.00
CeRep28 92 4 1.00 5 1.00
CeRep29 150 6 1.00 5 1.00
CeRep30 37 2 1.00 4 0.50
CeRep31 23 1 1.00 2 1.00
CeRep32 226 15 0.02 6 1.00
CeRep33 22 1 1.00 1 1.00
CeRep34 321 10 1.00 16 0.78
CeRep35 177 9 1.00 5 1.00
CeRep36 187 6 1.00 6 1.00
CeRep37 122 4 1.00 11 0.006
CeRep38 310 12 1.00 15 1.00
CeRep39 14 1 1.00 1 1.00
CeRep40 122 5 1.00 2 1.00
CeRep41 49 3 1.00 1 1.00
CeRep42 110 5 1.00 5 1.00
CeRep43 590 27 0.17 23 1.00
29 + 35 + 36 + 40 24 2 1.00 0 1.00
29/35/36/40 391 14 1.00 10 1.00
17 + 19 + 32 166 11 0.12 5 1.00
17/19/32 720 33 0.06 18 1.00
13 + 18 + 33 17 1 1.00 1 1.00
13/18/33 383 22 0.01 15 1.00
34 + 43 212 10 1.00 7 1.00
34/43 699 27 1.00 29 1.00
24 + 38 308 12 1.00 15 1.00
24/38 627 20 1.00 23 1.00
  • The number of translocation/transposition breakpoints in intergenic spacers containing a particular dispersed repeat was compared with the number of intergenic spacers in the genome containing that repeat. Only intergenic spacers of 10 kb or shorter were included, of which there are 16,574 in the Caenorhabditis elegansgenome. We tested whether breakpoints are associated with five compound repeats. For example, for the compound repeat CeRep19–CeRep32–CeRep17–CeRep19, we tested whether intergenic spacers containing breakpoints tend to contain all members of the repeat (17 + 19 + 32), or at least one member of this repeat (17/19/32). The P-values for one-sided χ2tests are given after applying the Bonferroni correction for multiple testing (multiplies the raw P-values by 43).

This Article

  1. Genome Res. 12: 857-867

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