Table 1.
Intracellular Localization and Antiviral Spectrum for Selected Mx Proteins
| Species | Gene | Accession no. | Size (aa) | Intracellular localization | Antiviral specificity | ||||||
| Virus | Family | ||||||||||
| Human | MxA | P20591 | 661 | Cytoplasm | Influenza virus, Thogoto virus | Orthomyxoviridae 1 | |||||
| Vesicular stomatitis virus | Rhabdoviridae 2 | ||||||||||
| Measles virus | Paramyxoviridae 3 | ||||||||||
| Hantaan virus | Bunyaviridae 4 | ||||||||||
| Coxsackievirus B4 | Picornaviridae | ||||||||||
| Semliki Forest virus | Togaviridae | ||||||||||
| MxB | P20592 | 715 | Nucleus and cytoplasm | Inactive | |||||||
| Mouse | Mx1 | P09922 | 631 | Nucleus | Influenza virus, Thogoto virus, Dhori virus | Orthomyxoviridae 1 | |||||
| Mx2 | NP_38634 | 655 | Cytoplasm | Vesicular stomatitis virus | Rhabdoviridae 2 | ||||||
| Hantaan virus | Bunyaviridae 4 | ||||||||||
| Rat | Mx1 | P18588 | 652 | Nucleus | Influenza virus, Thogoto virus | Orthomyxoviridae 1 | |||||
| Mx2 | P18589 | 659 | Cytoplasm | Vesicular stomatitis virus | Rhabdoviridae 2 | ||||||
| LaCrosse virus, Rift Valley fever virus | Bunyaviridae 4 | ||||||||||
| Mx3 | P18590 | 659 | Cytoplasm | Inactive | |||||||
| Chicken | Mx | Q92597 | 705 | Cytoplasm | Influenza virus | Orthomyxoviridae 1 | |||||
| Vesicular stomatitis virus | Rhabdoviridae 2 | ||||||||||
| Duck | Mx | P33238 | 721 | Nucleus and cytoplasm | Inactive | ||||||
