Transcriptional Regulation of the Stem Cell Leukemia Gene (SCL) — Comparative Analysis of Five Vertebrate SCL Loci

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Figure 4.
Figure 4.

: Conserved noncoding sequences from vertebrate SCL loci. (A) Alignment of the conserved sequences upstream of the poly(A) signal. The two predicted stem-loop structures, the AU-rich region and the poly(A) signal are indicated. (B) Alignment of the conserved sequences in exon 1. The conserved YY1 site is indicated. (C) Alignment of the conserved SCL promoter/enhancer sequences. The three motifs studied previously (SKN1 and two GATA sites) and the two newly identified conserved sequences (CS1 and CS2) are indicated. The vertical arrow indicates the transcriptional start site.

This Article

  1. Genome Res. 12: 749-759

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