Structure and Evolution of the Smith-Magenis Syndrome Repeat Gene Clusters, SMS-REPs

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Figure 5.
Figure 5.

Schematic representation of low-copy repeats (LCRs; >10 kb) in proximal 17p, including SMS and CMT1A chromosome regions. Colored boxes represent positions of highly similar sequence of LCR structures. Note that the at least 410-kb repeat, LCR17pA, flanking the proximal CMT1A-REP has three partial copies: LCR17pB, proximally adjacent to the middle SMS-REP, and LCR17pC and LCR17pD (also described as PSFS;Stankiewicz et al. 2001) flanking the proximal SMS-REP.

This Article

  1. Genome Res. 12: 729-738

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