Human metaphase chromosome 17 and G2 interphase nucleus after fluorescence in situ hybridization (FISH) with SMS-REP-specific bacterial artificial chromosome (BAC) RP11–158M20. To theleft is a human-chromosome-17 ideogram with the positions of hybridization signals (green) shown next to specific cytological bands. White horizontal arrows show specific locations of FISH signals with BACs containing the genomic segments listed above the arrows. To theright of the figure is a G2 interphase FISH analysis (the G2 phase of the nucleus was determined without an internal control probe). Note the three copies of SMS-REP (arrows in interphase nucleus) and SMS-REP-like sequences.
