Complex SNP-Based Haplotypes in Three Human Helicases: Implications for Cancer Association Studies

Table 5.

Allele Frequencies of SRN-Coding SNPs

cW1 cW3 cW4 cW6 cW7 cW8
T C G A T G T G C T T C
AfAm (N = 80) 0.54 0.46 0.97 0.03 0.51 0.49 0.64 0.36 0.85 0.15 0.86 0.14
Asian (N = 32) 0.8 0.2 1 0 0.54 0.46 0.5 0.5 0.82 0.18 0.87 0.13
Caucasian (N = 80) 0.72 0.28 0.91 0.09 0.47 0.53 0.47 0.53 0.77 0.23 0.69 0.31
Hispanic (N = 80) 0.75 0.25 0.91 0.09 0.54 0.46 0.54 0.46 0.72 0.28 0.82 0.18

  • N = number of chromosomes.

  • cW1 = c.744T > Ca, cW3 = c.1392G > Ab,c, cW4 = c.2592T > Ga, cW6 = c.3453T > Gb, cW7 = c.4314C > Ta, cW8 = c.4330T > Cd.

  • Castro et al. 1999.

  • Meisslitzer et al. 1997.

  • Vidal et al. 1998.

  • Ye et al. 1997.

This Article

  1. Genome Res. 12: 627-639

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