Gene3D: Structural Assignment for Whole Genes and Genomes Using the CATH Domain Structure Database

Table 3.

Description of the Major CATH Classes

Cath class Description
Class 1 all alpha helical protein domains
Class 2 all beta sheet protein domains
Class 3 alpha and beta protein domains
Class 4 domain with few secondary structure elements
Class 5 full PDB chains grouped into sequence families whose individual domains are classified within CATH classes 1–4
Class 6 single domain PDB chains that have not been classified within CATH classes 1–4
Class 7 full PDB chains grouped into sequence families whose individual domains are not classified within CATH classes 1–4
  • Classes 1–5 represent protein structures that have been fully classified within the CATH database. Classes 6 and 7 represent proteins that have been integrated into the database but have only completed the initial classification steps.

This Article

  1. Genome Res. 12: 503-514

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