Gene3D: Structural Assignment for Whole Genes and Genomes Using the CATH Domain Structure Database

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 1.
Figure 1.

An overview of the Gene3D server. (a) Genome Selection page. From here you can pick a genome to search. This brings up the assignment statistics page. Choosing ‘full’ also includes a summary of all the domains assigned to the genome. ‘Brief’ presents you with just the statistics. (b) Once a genome is selected, you get the statistics page. From here you can choose to search the genome using a keyword search; you can pick a gene from the list presented in the search results page (marked C). If you select a gene, you will go straight to that gene's domain assignments. (c) The Keyword search page. If you chose to search the genome using a key word (in this case, ‘uracil’), you will be presented with every gene in that genome which is associated with this key word. From here you can pick your gene of interest. (d) The assignment results page. If you chose a gene on the statistics page or on the search results page, you will be presented with the assignment results. These are presented as a diagram of the domain assignments (below the green hashed representation of the gene) and a summary of thePSI-BLAST results which led to this assignment (in the table below). From here you can link to the CATH database, the DHS, and PDBsum to gather further functional and structural information.

This Article

  1. Genome Res. 12: 503-514

Preprint Server