Oligonucleotide Arrays for High-Throughput SNPs Detection in the MHC Class I Genes: HLA-B as a Model System

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3.
Figure 3.

Procedure for analysis of hybridization data is illustrated for position 21–40 of exon 2. All oligonucleotide probes were assigned into one group and named B1 to B7 (refer to Table 1 for probes). The seven probes were spotted in quadruplicate. After hybridization, signal intensities were quantified, and signals with the highest intensities in this group (B5 and B7) were identified as positive.

This Article

  1. Genome Res. 12: 447-457

Preprint Server